the incidence of drug induced liver injury (dili) is about 1/1000 to 1/10000 among patients who receive therapeutic drug doses. drug induced hepatotoxicity is a major cause of acute and chronic liver disease. the severity of liver damage ranges from nonspecific changes in liver structure to acute liver failure, cirrhosis and liver cancer. some common agents that can cause liver injury are aceta...

conclusions hepatotoxicity of halogenated inhalational anesthetics has been well documented in available literature. halothane-induced liver injury was extensively acknowledged; however, the next generation halogenated anesthetics have different molecular structures and associated with less hepatotoxicity. although anesthesia-induced hepatitis is not a common occurrence, we must consider the as...

the protective effect of liquorice plant extract (lpe) on ccl4-induced hepatotoxicity in common carp was evaluated using fifty adult carps. the fish were cultured in a standard environment in terms of water flow rate, oxygen, ph, food and temperature. the fish were assigned into 5 groups (n = 10) as control, sham, and tests. the test groups were pre-treated for 3 h with various concentrations o...